Evidence supporting the use of: Ginseng, Panax
For the health condition: Cancer Treatment (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Panax ginseng has been investigated as an adjunct in cancer treatment, primarily for its potential to reduce cancer-related fatigue, improve quality of life, and mitigate some side effects of chemotherapy. Several randomized controlled trials and systematic reviews suggest that ginseng, particularly Panax ginseng and American ginseng, may modestly alleviate cancer-related fatigue—a common and debilitating side effect of cancer and its treatments. For example, a 2013 randomized clinical trial published in the Journal of the National Cancer Institute found that high-dose American ginseng improved fatigue in cancer patients over eight weeks compared to placebo.

Ginsenosides, the primary active compounds in Panax ginseng, are thought to exert anti-inflammatory and adaptogenic effects, which may contribute to their benefits in this context. However, evidence for other cancer treatment side effects, such as nausea, neuropathy, or immune suppression, is limited and inconclusive. Most clinical studies have focused on fatigue, and while some results are promising, the magnitude of benefit is generally modest, and methodological quality varies.

Professional organizations such as the American Society of Clinical Oncology (ASCO) recognize that ginseng may be helpful for fatigue but do not broadly endorse it for other cancer treatment side effects. Importantly, ginseng may interact with some cancer therapies and medications, so patients should consult their healthcare providers before use. Overall, the evidence is preliminary and supports only a cautious, adjunctive role for Panax ginseng in reducing certain cancer treatment side effects, particularly fatigue.

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Products containing Ginseng, Panax

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