Evidence supporting the use of: Ginseng (unspecified)
For the health condition: Cancer Treatment (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginseng, particularly Panax ginseng and American ginseng, has been explored as a complementary therapy to reduce side effects associated with cancer treatment, such as fatigue. Several clinical studies and systematic reviews have investigated its efficacy, with some evidence suggesting benefit, especially in managing cancer-related fatigue. For example, a randomized controlled trial published in the Journal of the National Cancer Institute (Barton et al., 2013) found that American ginseng significantly improved fatigue in cancer patients compared to placebo. Some smaller studies also report potential benefits for mood and quality of life, but results are inconsistent and often limited by methodological weaknesses.

Mechanistically, ginseng is thought to exert adaptogenic and anti-inflammatory effects, which could theoretically mitigate some chemotherapy-induced symptoms. However, there is limited evidence supporting its use for other side effects such as nausea, neuropathy, or immune suppression. The overall quality of evidence remains moderate to low due to small sample sizes, variations in ginseng preparations, and short duration of studies.

Major cancer organizations (like the American Cancer Society) recognize that ginseng may help with fatigue but do not recommend it broadly due to insufficient high-quality data and potential drug interactions. Thus, while there is some scientific support for the use of ginseng to reduce cancer treatment side effects, particularly fatigue, more rigorous studies are needed.

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Products containing Ginseng (unspecified)

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