Evidence supporting the use of: Sophora
For the health condition: Cancer Treatment (reducing side effects)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sophora (referring generally to the genus, which includes species like Sophora flavescens or "Ku Shen") has a long history of use in traditional Chinese medicine. In this context, Sophora species have been incorporated into herbal formulas aimed at reducing the side effects of cancer treatments such as chemotherapy and radiotherapy. Traditional practitioners believe compounds in Sophora can help "clear heat," detoxify the body, and support immune function, which are thought to help patients cope better with cancer therapies. However, while these uses are deeply rooted in traditional practices, there is limited direct scientific evidence from robust clinical trials validating these claims. Some preclinical studies have explored the anti-inflammatory and cytoprotective effects of Sophora constituents, such as matrine and oxymatrine, but clinical data specifically demonstrating reduced side effects from cancer treatments in humans is lacking or inconclusive. Therefore, while the use is justified by tradition and some pharmacological rationale, its efficacy and safety for this indication require more rigorous scientific validation.

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Products containing Sophora

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