Evidence supporting the use of: Scabrous Gentian
For the health condition: Canker Sores

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Scabrous Gentian (Gentiana scabra) has a long history of use in traditional Chinese medicine (TCM), particularly for its purported anti-inflammatory, detoxifying, and heat-clearing properties. Within TCM, it is sometimes used as part of herbal formulas intended to address “mouth ulcers” or “oral sores,” which may include canker sores (aphthous ulcers). The rationale is based on the TCM concept of clearing “heat” or “damp-heat” from the body, which is believed to manifest as oral ulcerations. However, there is very limited direct scientific evidence specifically evaluating Scabrous Gentian for the treatment of canker sores. Some in vitro and animal studies indicate that Gentiana scabra extracts possess anti-inflammatory and antimicrobial activities, which could, in theory, help with oral lesions, but clinical trials in humans for this specific indication are lacking. The use of Scabrous Gentian for canker sores is therefore primarily justified by tradition rather than robust scientific validation. Most references to its effectiveness come from herbal compendia, case reports, and empirical usage in TCM, rather than peer-reviewed clinical studies. As such, while it is a traditional remedy for mouth ulcers in East Asian medicine, the evidence supporting its use for canker sores should be considered preliminary and not definitive.

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Products containing Scabrous Gentian

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