Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Benfotiamine is a lipid-soluble derivative of thiamine (vitamin B1) that has been studied for its potential to protect the vascular system, particularly small blood vessels (capillaries), from damage associated with high blood sugar and oxidative stress. Scientific interest in benfotiamine for capillary support is grounded in its role in reducing the formation of advanced glycation end products (AGEs) and inhibiting several biochemical pathways implicated in diabetic microvascular complications.

Clinical trials and preclinical studies have shown that benfotiamine supplementation can reduce markers of endothelial dysfunction and microvascular damage, particularly in individuals with diabetes. For example, several randomized controlled trials have demonstrated that benfotiamine may help improve endothelial function and decrease albuminuria (a marker of capillary leakage in the kidneys) in diabetic patients. Animal studies also suggest that benfotiamine may prevent diabetic retinopathy and neuropathy, both of which involve damage to capillaries.

However, while the evidence is promising, it is not yet conclusive. Most studies are small, short-term, or focus on populations with diabetes, and there is limited data on its effects in healthy individuals or in the context of other capillary disorders. Nevertheless, the mechanistic rationale and preliminary clinical data provide moderate scientific support for the use of benfotiamine in supporting capillary health, especially in situations of heightened oxidative stress or glycemic burden.

More about Benfotiamine
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Other body systems supported by Benfotiamine

Blood
Brain
Capillaries
Circulatory System
Heart
Nerves

Products containing Benfotiamine

We currently have no products on Vitabase that contain this ingredient.