Evidence supporting the use of: Bioflavonoids (mixture)
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Bioflavonoids, also known as flavonoids, are a diverse group of plant compounds found abundantly in fruits and vegetables. Their use to support capillary health is primarily justified by scientific research, although some historical use exists. Flavonoids such as rutin, hesperidin, and quercetin have been studied for their potential effects on capillary strength and function. Several clinical and experimental studies have shown that certain bioflavonoids can reduce capillary permeability and fragility, particularly in conditions like chronic venous insufficiency and hemorrhoids. The mechanism is thought to involve antioxidant effects, inhibition of enzymes that degrade connective tissue, and anti-inflammatory properties.
For example, randomized controlled trials have demonstrated that micronized purified flavonoid fractions (MPFF), which contain diosmin and hesperidin, can decrease symptoms such as leg swelling and improve capillary resistance in patients with venous disorders. Rutin, another flavonoid, has been reported to decrease capillary fragility in people with conditions like hypertension or diabetes, though results are variable. Overall, while there is moderate scientific support for bioflavonoids benefiting capillary health, especially as part of specific formulations for vascular disorders, the evidence is not uniform across all types of bioflavonoids or all populations. Therefore, the evidence rating stands at 3 out of 5.
Other ingredients that support Capillaries
alpha-glycosyl isoquercitrinanthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
l-arginine
nattokinase
orange
phenolic acids
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
water
capsicum
lingzhi
yarrow
yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
Asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Baikal Skullcap
Baicalein
Benfotiamine
berry
Bioflavonoids
Coumarin
Centella triterpenes
Cyanidin
Citrus
Centella asiatica
Coca
Capers
cypress
Cranesbill
Collinsonia
Diosmin
Danshen
Delphinidin
Dextran
Diosmetin
epicatechin
Erigeron
Eicosapentaenoic Acid
Escin
Flavonoids
Flavonones
Periwinkle
Other body systems supported by Bioflavonoids (mixture)
ArteriesBlood
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Liver
Skin
Veins