Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Centella asiatica (commonly known as gotu kola) is traditionally used in many cultures for wound healing and circulatory support. In recent decades, scientific research has specifically examined its effects on the capillaries and microcirculation. Several clinical studies and reviews support its use for chronic venous insufficiency, a condition related to compromised capillary function, and for improving symptoms such as edema, heaviness, and pain in the legs.

The active compounds in Centella asiatica, primarily triterpenoids such as asiaticoside and madecassoside, have been shown to enhance collagen synthesis and strengthen the walls of blood vessels. This is believed to increase capillary resistance and reduce capillary permeability, thereby decreasing leakage and swelling. Several randomized controlled trials have found statistically significant benefits in objective markers of microcirculation (such as transcapillary filtration rate) and subjective symptoms in patients with venous disease.

Systematic reviews and meta-analyses (see: Belcaro et al., 2013; Maquart et al., 1999) confirm that Centella asiatica extracts (often standardized as TTFCA—total triterpenic fraction of Centella asiatica) can benefit microcirculatory health, particularly in the context of venous hypertension and associated capillary dysfunctions. While more large-scale, high-quality studies could further clarify the effects, the existing scientific evidence gives a strong rationale for its use to support the capillary system.

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Other ingredients that support Capillaries

alpha-glycosyl isoquercitrin
anthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
Nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
Water
capsicum
lingzhi
Yarrow
Yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
apocynin
astragalin
Baikal Skullcap
baicalein
benfotiamine
berry
bioflavonoids
coumarin
Centella triterpenes
cyanidin
Citrus
Centella asiatica
coca
capers
cypress
cranesbill
Collinsonia
Diosmin
danshen
delphinidin
dextran
diosmetin
epicatechin
Erigeron
eicosapentaenoic acid
escin
fruit
flavonoids
fatty acids
flavanones
Fagopyrum
flavoglycosides
flavans
flavonones
flavanols
flavones
Gypenoside
ginkgolides
ginkgo flavone glycoside
Ginkgoside
ginkgoheteroside
Hyperoside
Immortelle
linden
Ligustrazin
leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
pagoda tree
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
proanthocyanidins
Periwinkle
punicalagins
Pycnogenol
polymethoxylated flavones
rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
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Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry

Other body systems supported by Centella asiatica

Brain
Capillaries
Circulatory System
Digestive System
Gastrointestinal Tract
Immune System
Joints
Liver
Nerves
Skin
Veins

Products containing Centella asiatica

We currently have no products on Vitabase that contain this ingredient.