Evidence supporting the use of: Epicatechin
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epicatechin is a flavonoid found in foods such as cocoa, green tea, and certain fruits. Its use to support capillary health is primarily based on its biological activity as an antioxidant and its effects on endothelial function. Scientific studies have shown that epicatechin can enhance nitric oxide production, leading to improved vasodilation and endothelial health, which are important for maintaining healthy microcirculation and capillary function.

A number of animal and in vitro studies have demonstrated that epicatechin can protect endothelial cells from oxidative stress and inflammation, both of which can compromise capillary integrity. Human studies, though limited, have shown improved endothelial-dependent vasodilation after cocoa or epicatechin supplementation, suggesting a potential benefit for capillary function. However, most clinical trials focus on broader vascular health rather than capillaries specifically, and there is a lack of direct evidence for epicatechin’s effect on capillary fragility or permeability in humans.

In summary, while there is scientific rationale and some supportive data for epicatechin's vascular benefits, the evidence specifically supporting its use for capillary health is relatively weak and indirect. More targeted clinical research would be needed to justify a higher rating.

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Products containing epicatechin

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