Evidence supporting the use of: Epicatechin
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Epicatechin is a flavonoid found in foods such as cocoa, green tea, and certain fruits. Its use to support capillary health is primarily based on its biological activity as an antioxidant and its effects on endothelial function. Scientific studies have shown that epicatechin can enhance nitric oxide production, leading to improved vasodilation and endothelial health, which are important for maintaining healthy microcirculation and capillary function.
A number of animal and in vitro studies have demonstrated that epicatechin can protect endothelial cells from oxidative stress and inflammation, both of which can compromise capillary integrity. Human studies, though limited, have shown improved endothelial-dependent vasodilation after cocoa or epicatechin supplementation, suggesting a potential benefit for capillary function. However, most clinical trials focus on broader vascular health rather than capillaries specifically, and there is a lack of direct evidence for epicatechin’s effect on capillary fragility or permeability in humans.
In summary, while there is scientific rationale and some supportive data for epicatechin's vascular benefits, the evidence specifically supporting its use for capillary health is relatively weak and indirect. More targeted clinical research would be needed to justify a higher rating.
Other ingredients that support Capillaries
Aescinalpha-glycosyl isoquercitrin
anthocyanidins
anthocyanins
anthocyanosides
apocynin
apple
Aronia melanocarpa
ashitaba
asiaticoside
astragalin
astragalus
baicalein
Baikal Skullcap
benfotiamine
berry
bilberry
bioflavonoids
black currant
blueberry
butcher's broom
capers
capsicum
cayenne pepper
Centella asiatica
Centella triterpenes
Chinese salvia root
chokeberry
Citrus
citrus bioflavonoids
coca
Collinsonia
coumarin
cranesbill
cyanidin
cypress
danshen
delphinidin
dextran
diosmetin
Diosmin
eicosapentaenoic acid
epicatechin
Erigeron
escin
Fagopyrum
fatty acids
fish oil
flavanols
flavanones
flavans
flavoglycosides
flavones
flavonoids
flavonols
flavonones
fruit
garlic bulb
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
gotu kola
grape
Gypenoside
hawthorn
herbal blend (proprietary)
hesperidin
horse chestnut
Hyperoside
Immortelle
Japanese sophora
L-arginine
leucoanthocyanidins
Ligusticum
Ligustrazin
linden
lingzhi
Mineral ascorbate
Nattokinase
Oligomeric proanthocyanidins
onion
orange
pagoda tree
Pentacyclic triterpenoids
Periwinkle
phenolic compounds
Phenylpropanoids
Phosphate ascorbate
pine bark
Polydatin
polymethoxylated flavones
polyphenols
prickly ash
proanthocyanidins
procyanidin
procyanidol
punicalagins
purslane
Pycnogenol
quercetin
rue
Ruscogenins
Ruscus
rutin
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
shepherd's purse
Stone Root
Sweet Clover
Taxifolin
terpene lactones
Terpenoids
Troxerutin
Vincamine
vitamin B
vitamin C
vitamin E
vitamin K
Vitexin
Witch Hazel
Xantinol Nicotinate
Yarrow
Yarrow
Yumberry
Other body systems supported by epicatechin
ArteriesBlood
Brain
Capillaries
Circulatory System
Heart
Intestinal System
Muscles
Skin
