Evidence supporting the use of: Flavonoid
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Flavonoids are a class of polyphenolic compounds found abundantly in fruits, vegetables, and certain beverages like tea and wine. Their use to support capillary health is primarily justified by scientific evidence. Flavonoids have been shown in multiple studies to strengthen capillary walls, reduce capillary fragility, and improve microcirculation. One of the best-studied flavonoids in this context is diosmin, often used in combination with hesperidin. Clinical trials and meta-analyses have demonstrated that these compounds can reduce symptoms of chronic venous insufficiency, such as leg swelling, heaviness, and discomfort. The mechanism is thought to involve antioxidant activity, inhibition of inflammatory mediators, and direct effects on vascular endothelium, leading to improved tone and permeability of capillaries. Additionally, flavonoids like rutin and quercetin have demonstrated similar protective effects on capillaries in both animal and human studies. While not all flavonoids have the same potency or efficacy, the overall body of evidence supports their role in maintaining capillary integrity and function. However, while the evidence is robust for certain flavonoids, it is not universal across all compounds in this class, and results can vary based on formulation, dosage, and individual response.
Other ingredients that support Capillaries
alpha-glycosyl isoquercitrinanthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
water
capsicum
lingzhi
yarrow
yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
Asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Baikal Skullcap
Baicalein
Benfotiamine
berry
Bioflavonoids
Coumarin
Centella triterpenes
Cyanidin
Citrus
Centella asiatica
Coca
Capers
cypress
Cranesbill
Collinsonia
Diosmin
Danshen
Delphinidin
Dextran
Diosmetin
epicatechin
Erigeron
Eicosapentaenoic Acid
Escin
Fruit
Flavonoids
Fatty acids
Flavanones
Fagopyrum
Flavoglycosides
Flavans
Flavonones
Flavanols
Flavones
Gypenoside
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
Ginkgoheteroside
Hyperoside
Immortelle
Linden
Ligustrazin
Leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
Pagoda Tree
Procyanidol
Procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
Proanthocyanidins
Periwinkle
Punicalagins
Pycnogenol
Polymethoxylated flavones
Rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry