Evidence supporting the use of: Flavonoid (mixture)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Flavonoids, a diverse group of phytonutrients found in fruits, vegetables, and certain beverages, have a well-documented role in supporting capillary health, primarily due to their antioxidant and anti-inflammatory properties. Scientific studies have shown that flavonoid mixtures, particularly those containing rutin, diosmin, hesperidin, and quercetin, can strengthen capillary walls, reduce capillary permeability, and improve microcirculation. These effects are especially significant in conditions like chronic venous insufficiency and hemorrhoids, where capillary fragility is a concern.

Clinical trials and meta-analyses have demonstrated that flavonoid supplementation can decrease symptoms such as edema, leg heaviness, and capillary bleeding. Mechanistically, flavonoids inhibit enzymes that degrade connective tissue, reduce inflammatory mediators, and scavenge free radicals that contribute to vascular damage. The European Medicines Agency and other health authorities recognize certain flavonoids, such as diosmin and hesperidin, for their vascular-protective effects.

Though not all flavonoid mixtures are identical or equally studied, there is a substantial and growing body of scientific evidence supporting the use of specific flavonoid combinations for maintaining capillary integrity and function. Therefore, the use of flavonoid mixtures for capillary support is justified by scientific evidence, with an evidence strength rating of 4 out of 5.

More about Flavonoid (mixture)
More about Capillaries

Other ingredients that support Capillaries

alpha-glycosyl isoquercitrin
anthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
Nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
Water
capsicum
lingzhi
Yarrow
Yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
apocynin
astragalin
Baikal Skullcap
baicalein
benfotiamine
berry
bioflavonoids
coumarin
Centella triterpenes
cyanidin
Citrus
Centella asiatica
coca
capers
cypress
cranesbill
Collinsonia
Diosmin
danshen
delphinidin
dextran
diosmetin
epicatechin
Erigeron
eicosapentaenoic acid
escin
fruit
flavonoids
fatty acids
flavanones
Fagopyrum
flavoglycosides
flavans
flavonones
flavanols
flavones
Gypenoside
ginkgolides
ginkgo flavone glycoside
Ginkgoside
ginkgoheteroside
Hyperoside
Immortelle
linden
Ligustrazin
leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
pagoda tree
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
proanthocyanidins
Periwinkle
punicalagins
Pycnogenol
polymethoxylated flavones
rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry

Products containing Flavonoid (mixture)

We currently have no products on Vitabase that contain this ingredient.