Evidence supporting the use of: Flavonones
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavonones are a subclass of flavonoids, naturally occurring compounds found in various fruits and vegetables, especially citrus fruits. There is scientific evidence supporting their role in supporting capillary health and vascular function. Flavonones such as hesperidin, naringin, and eriocitrin have been studied for their effects on capillary permeability and fragility. Clinical and preclinical studies suggest that flavonones may help strengthen capillary walls, reduce inflammation, and improve microcirculation, primarily through their antioxidant and anti-inflammatory properties.

A number of studies, especially in Europe, have evaluated hesperidin (often in combination with diosmin, another flavonoid) for the treatment of chronic venous insufficiency and capillary fragility, with results indicating a reduction in capillary permeability and an improvement in symptoms such as edema and bruising. The mechanism is thought to involve inhibition of enzymes that degrade connective tissue in capillary walls and scavenging of reactive oxygen species. While the evidence is moderate and often based on mixed formulations rather than isolated flavonones, the overall scientific consensus supports a beneficial effect on capillary health.

Therefore, the use of flavonones to support the capillary body system is justified by scientific findings, though more research is warranted for definitive conclusions regarding specific compounds and dosages.

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