Evidence supporting the use of: Ginkgolide A
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Ginkgolide A is a terpene lactone found in the leaves of the Ginkgo biloba tree. It is one of several ginkgolides present in standardized Ginkgo biloba extracts, which have been the subject of research regarding vascular health, including effects on capillaries. Scientific studies have shown that Ginkgo biloba extracts can improve microcirculation by promoting vasodilation, reducing blood viscosity, and exerting antioxidant effects on blood vessels. These actions may support capillary health, particularly in conditions characterized by impaired microvascular flow, such as peripheral vascular disease or age-related cognitive decline.
However, most studies utilize standardized Ginkgo biloba extracts containing a combination of ginkgolides (A, B, C, etc.), bilobalide, and flavonoids, rather than isolated Ginkgolide A. The specific effects of isolated Ginkgolide A on capillaries are less well-studied; much of the available evidence relates to Ginkgolide B as a platelet-activating factor (PAF) antagonist. While it is plausible that Ginkgolide A contributes to the overall vascular benefits observed with Ginkgo biloba preparations, direct clinical evidence specifically linking Ginkgolide A to capillary support is limited.
In summary, while there is some scientific basis—mainly from studies on Ginkgo biloba extracts—for supporting capillary function, the evidence specifically for Ginkgolide A is modest and indirect. Thus, the overall scientific support for this specific use is rated as low to moderate.
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bilberry
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butcher's broom
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chokeberry
citrus bioflavonoids
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polyphenols
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