Evidence supporting the use of: Nitrate
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Nitrate, primarily found in leafy green vegetables and beetroot, is scientifically recognized for its role in supporting vascular health, including the capillaries. When ingested, dietary nitrate is converted in the body to nitrite and then to nitric oxide (NO), a molecule well known for its vasodilatory effects. Nitric oxide relaxes the smooth muscle in blood vessels, resulting in improved blood flow and reduced blood pressure. While most research focuses on the effects of nitrate on larger arteries and overall vascular function, some studies suggest that enhanced NO bioavailability can also support microcirculation, which includes the capillary network.
Clinical trials have demonstrated that dietary nitrate supplementation can improve endothelial function, which encompasses the health of both large and small blood vessels. For example, beetroot juice supplementation has been shown to increase microvascular blood flow in humans. However, while the evidence supporting nitrate’s role in supporting general vascular health is robust, direct evidence specifically targeting “capillary support” is still emerging and less comprehensive. Thus, nitrate is considered scientifically validated for general vascular health, with moderate evidence for direct capillary benefits.
In summary, nitrate is scientifically validated for supporting vascular function, with some promising but not yet definitive evidence for direct capillary support, justifying a moderate evidence rating.
Other ingredients that support Capillaries
alpha-glycosyl isoquercitrinanthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
l-arginine
nattokinase
orange
phenolic acids
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
water
capsicum
lingzhi
yarrow
yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
Asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Baikal Skullcap
Baicalein
Benfotiamine
berry
Bioflavonoids
Coumarin
Centella triterpenes
Cyanidin
Citrus
Centella asiatica
Coca
Capers
cypress
Cranesbill
Collinsonia
Diosmin
Danshen
Delphinidin
Dextran
Diosmetin
epicatechin
Erigeron
Eicosapentaenoic Acid
Escin
Flavonoids
Flavonones
Periwinkle
Other body systems supported by Nitrate
ArteriesBlood
Brain
Capillaries
Circulatory System
Heart
Muscles
Respiratory System
Veins