Evidence supporting the use of: Phenylpropanoids
For the body system: Capillaries

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phenylpropanoids are a diverse class of plant secondary metabolites, which include compounds such as cinnamic acid, coumarins, and lignans. Their use in supporting capillary health is primarily rooted in traditional herbal medicine, particularly in European and Asian phytotherapy. Certain phenylpropanoid-rich plants, such as horse chestnut (Aesculus hippocastanum) and butcher’s broom (Ruscus aculeatus), have a long history of use for supporting vascular health, including capillary strength and integrity. The rationale is based on observed effects such as reduced capillary fragility, improved microcirculation, and decreased edema, likely due to anti-inflammatory and vasoprotective actions of some phenylpropanoids.

However, the term "phenylpropanoids (unspecified)" is broad, and not all phenylpropanoids have been studied for these effects. Some specific compounds, such as aescin (from horse chestnut), have limited clinical evidence supporting their benefits for capillary and venous health, but direct scientific validation for the entire class or for "unspecified" phenylpropanoids is lacking. Most modern references to their use for capillary support are based on traditional practices rather than robust clinical trials. Therefore, while there is a traditional basis for their use, scientific evidence is limited and the overall strength of evidence is moderate at best.

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