Evidence supporting the use of: Polyphenols (various)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols, a diverse group of naturally occurring compounds found in plants (such as flavonoids, phenolic acids, and stilbenes), have received considerable scientific attention for their potential vascular benefits, including capillary protection and support. Research indicates that polyphenols exhibit antioxidant, anti-inflammatory, and vasoprotective properties, which may contribute to maintaining capillary integrity and function. Flavonoids, a major subclass of polyphenols (e.g., diosmin, hesperidin, quercetin, and rutin), have been specifically studied for their ability to strengthen capillary walls, reduce capillary permeability, and improve microcirculation. Clinical trials, particularly with flavonoid-rich extracts, suggest benefits in reducing symptoms of chronic venous insufficiency and capillary fragility, such as bruising and edema. For example, a double-blind trial published in the International Angiology journal reported improved capillary resistance in subjects using specific citrus bioflavonoids. However, while laboratory and some clinical data support these effects, evidence is not uniform across all types of polyphenols, and much of the positive data is associated with isolated or concentrated flavonoids rather than the entire class of polyphenols. Thus, while there is scientific validation for the use of certain polyphenols in supporting capillary health, the strength of evidence varies by compound, preparation, and clinical context.

More about polyphenols (various)
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