Evidence supporting the use of: Proanthocyanidin (unspecified)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Proanthocyanidins are a class of polyphenols found in many plants, notably in grape seeds, pine bark, and certain berries. They are known for their antioxidant properties and have been studied for their effects on the vascular system, including capillaries. Scientific research suggests that proanthocyanidins can help strengthen capillary walls, reduce capillary permeability, and improve microcirculation. Several clinical studies—especially with grape seed extract (rich in proanthocyanidins)—have shown benefits in conditions characterized by capillary fragility, such as chronic venous insufficiency and edema. Their mechanism of action appears to involve stabilizing collagen and elastin, key structural proteins in blood vessel walls, and scavenging free radicals that can damage vascular tissues. For example, a meta-analysis published in "Phytotherapy Research" (2016) found that oligomeric proanthocyanidins significantly improved symptoms of chronic venous insufficiency, likely via capillary support. However, while the evidence is promising, much of it is based on extracts where proanthocyanidin content is specified, and data on "unspecified" proanthocyanidins are less robust. Therefore, the scientific evidence for capillary support is moderate (3/5) and strongest when the source and dosage are clearly identified.

More about Proanthocyanidin (unspecified)
More about Capillaries

Other ingredients that support Capillaries

alpha-glycosyl isoquercitrin
anthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
water
capsicum
lingzhi
yarrow
yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
Asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Baikal Skullcap
Baicalein
Benfotiamine
berry
Bioflavonoids
Coumarin
Centella triterpenes
Cyanidin
Citrus
Centella asiatica
Coca
Capers
cypress
Cranesbill
Collinsonia
Diosmin
Danshen
Delphinidin
Dextran
Diosmetin
epicatechin
Erigeron
Eicosapentaenoic Acid
Escin
Fruit
Flavonoids
Fatty acids
Flavanones
Fagopyrum
Flavoglycosides
Flavans
Flavonones
Flavanols
Flavones
Gypenoside
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
Ginkgoheteroside
Hyperoside
Immortelle
Linden
Ligustrazin
Leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
Pagoda Tree
Procyanidol
Procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
Proanthocyanidins
Periwinkle
Punicalagins
Pycnogenol
Polymethoxylated flavones
Rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry

Products containing Proanthocyanidin (unspecified)

We currently have no products on Vitabase that contain this ingredient.