Evidence supporting the use of: Resveratrol conjugates (mixed)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Resveratrol conjugates (mixed) are used to support capillary health primarily based on scientific evidence, though the evidence is moderate rather than definitive. Resveratrol is a polyphenolic compound found in grapes, berries, and peanuts. In the body, it is rapidly metabolized to various conjugates (mainly glucuronides and sulfates), which circulate at higher concentrations than free resveratrol. Scientific studies suggest that resveratrol and its conjugates have antioxidant and anti-inflammatory properties that may protect endothelial cells and capillary walls from oxidative damage and inflammation. Preclinical studies and animal models have indicated that resveratrol can improve microcirculation, reduce capillary leakage, and enhance endothelial function. Some small human studies and in vitro data also support its ability to modulate nitric oxide production and inhibit platelet aggregation, both of which are important for capillary health. However, most clinical data are limited in size and duration, and it remains unclear whether the conjugated forms in human plasma exert the same benefits as free resveratrol seen in experimental models. Overall, while resveratrol conjugates are not a traditional remedy for capillary support, there is moderate scientific rationale and emerging evidence for their beneficial role in supporting capillary integrity and function, warranting further investigation.

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