Evidence supporting the use of: Rue
For the body system: Capillaries

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rue (Ruta graveolens) has a long history of use in traditional herbal medicine, including European folk medicine, where it was employed for a variety of ailments. One traditional application was to support capillary health and reduce capillary fragility—likely due to its perceived ability to enhance blood circulation and reduce bruising. Historic herbal texts mention rue as a remedy for "weak blood vessels" and to "strengthen the capillaries," especially in the context of varicose veins or easy bruising. These uses were based largely on empirical observation rather than clinical research.

Scientifically, rue contains several bioactive compounds, such as rutin and other flavonoids, which are known to have some effects on capillary permeability and vascular strength. Rutin, for example, has been studied for its potential to support capillary integrity. However, while rutin itself is validated in some studies, there is limited direct clinical evidence that the whole rue plant or its extracts significantly benefit capillary health in humans. Additionally, rue can be toxic in higher doses and is not widely recommended in modern phytotherapy for this purpose.

In summary, rue's use for capillary support is rooted mainly in tradition, with a modest foundation in the presence of bioactive constituents, but lacks robust scientific validation for this specific application.

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