Evidence supporting the use of: Ruscogenins
For the body system: Capillaries

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ruscogenins are steroidal saponins found in the roots of Ruscus aculeatus (butcher’s broom), a plant traditionally used in Europe for vascular health. There is moderate scientific evidence supporting the use of ruscogenins for supporting capillary function and venous circulation. Experimental studies suggest that ruscogenins exert venotonic and anti-inflammatory effects, which may help stabilize capillary walls and reduce capillary permeability. These effects are believed to be mediated through inhibition of elastase and hyaluronidase enzymes, reduction of vascular permeability, and improvement of lymphatic drainage. Several placebo-controlled clinical trials and reviews have reported that extracts containing ruscogenins can reduce symptoms of chronic venous insufficiency, such as leg swelling, heaviness, and discomfort, which are linked to capillary integrity and function. However, the number of large, high-quality trials is limited, and most studies use whole plant extracts rather than isolated ruscogenins, making it difficult to fully attribute the effects solely to ruscogenins. The European Medicines Agency acknowledges the traditional and some scientific support for butcher’s broom in improving symptoms of venous insufficiency. In summary, while there is a reasonable scientific rationale and some clinical evidence for the capillary-supporting effects of ruscogenins, more rigorous and targeted studies are needed to confirm their efficacy and clarify their specific role.

More about Ruscogenins
More about Capillaries

Other body systems supported by Ruscogenins

Arteries
Capillaries
Circulatory System
Lymphatics
Veins

Products containing Ruscogenins

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