Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Terpene lactones, particularly those found in Ginkgo biloba extracts (notably ginkgolides and bilobalide), have been studied for their effects on the circulatory system, including capillary health. Scientific research indicates that these compounds exhibit several pharmacological actions relevant to the microvasculature. They have been shown to inhibit platelet-activating factor (PAF), which helps reduce blood viscosity and improve microcirculation, potentially supporting the function and integrity of capillaries. Clinical trials and meta-analyses investigating Ginkgo biloba extracts (standardized to contain terpene lactones) have reported improvements in peripheral circulation and symptoms of chronic cerebrovascular insufficiency, such as memory disturbances and vertigo, which are believed to be partially mediated by improved capillary perfusion.

However, while these effects are promising, the direct evidence specifically linking terpene lactones to enhanced capillary structure or function in humans is moderate. The majority of studies focus on general microcirculatory effects and symptom improvement rather than direct measurement of capillary health. Thus, the evidence base supports their use for promoting microvascular function, with a moderate level of scientific validation, but further research is needed to clarify their specific impact on capillaries.

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