Evidence supporting the use of: Vitamin C (ascorbyl palmitate)
For the body system: Capillaries

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C, including its fat-soluble ester form ascorbyl palmitate, is used to support capillary health based on its well-established role in collagen synthesis and vascular integrity. Scientific studies have shown that vitamin C is essential for the hydroxylation of proline and lysine, two amino acids crucial for stable collagen formation. Collagen is a major structural protein in blood vessels, and its proper synthesis is required for maintaining capillary strength and function. Deficiency in vitamin C leads to weakened capillaries, resulting in symptoms such as easy bruising and bleeding gums, as seen in scurvy.

Most research is based on ascorbic acid, but ascorbyl palmitate is a commonly used fat-soluble derivative that can be incorporated into cellular membranes, potentially providing antioxidant protection in lipid environments. Studies in vitro and in animal models have demonstrated that vitamin C and its derivatives can protect endothelial cells (which line blood vessels) from oxidative stress, helping to preserve capillary function. However, there is limited direct clinical evidence specifically on ascorbyl palmitate for capillary health in humans; most data extrapolate findings from ascorbic acid studies.

Overall, the evidence for vitamin C’s role in supporting capillaries is scientifically validated, though the specific contribution of ascorbyl palmitate compared to ascorbic acid is less well studied. The rating of 3 reflects strong mechanistic and deficiency-based evidence, but a relative lack of direct clinical trials with ascorbyl palmitate as the sole intervention.

More about Vitamin C (ascorbyl palmitate)
More about Capillaries

Other body systems supported by Vitamin C (ascorbyl palmitate)

Adrenal Cortex
Adrenal Glands
Arteries
Capillaries
Gums
Immune System
Mucus Membranes
Skin

Products containing Vitamin C (ascorbyl palmitate)

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