Evidence supporting the use of: Vitamin C (sodium ascorbate)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin C (sodium ascorbate) has substantial scientific validation for its role in supporting capillary health. Vitamin C is essential for the biosynthesis of collagen, a critical structural protein for blood vessel integrity, including the capillaries. Deficiency in vitamin C leads to weakened capillary walls, resulting in increased fragility and permeability—a hallmark of scurvy. Numerous studies have demonstrated that adequate vitamin C intake helps maintain endothelial function and capillary strength by supporting the synthesis and cross-linking of collagen fibers. Additionally, vitamin C acts as an antioxidant, protecting the endothelial cells lining the capillaries from oxidative stress, which can otherwise contribute to microvascular damage. Clinical evidence shows that supplementation with vitamin C can reduce capillary fragility and permeability in populations at risk for deficiency, such as the elderly or individuals with chronic illnesses. While there is robust evidence for the prevention of deficiency-related capillary problems, research on vitamin C supplementation in healthy individuals for further strengthening already normal capillaries is less definitive, but still suggests a beneficial role. Overall, the use of vitamin C (including sodium ascorbate) to support the capillaries is well-founded on both physiological mechanisms and clinical observations.

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