Evidence supporting the use of: Vitamin E (vitamin E acetate)
For the body system: Capillaries

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, including its common supplement form vitamin E acetate (tocopheryl acetate), is used to support capillary health primarily due to its antioxidant properties. Scientific evidence suggests that vitamin E can help protect the integrity of blood vessels, including capillaries, by neutralizing free radicals and reducing oxidative stress—factors involved in capillary fragility and microvascular dysfunction. Some studies have shown that vitamin E supplementation can decrease capillary permeability and fragility, particularly in populations with deficiencies or increased oxidative stress, such as individuals with diabetes or chronic venous insufficiency. For example, early clinical research and animal studies demonstrated that vitamin E could help stabilize vascular walls and prevent leakage from capillaries. However, large-scale, high-quality clinical trials directly linking vitamin E supplementation to improved capillary health in the general population are limited, and the evidence is not entirely consistent.

Overall, while the use of vitamin E to support capillary health has some basis in mechanistic and preliminary clinical research, it is not among the most strongly established uses, and not all studies show clear benefits. Therefore, the scientific evidence is moderate (rated 3), and further research is needed to clarify its role and effectiveness for supporting capillary function specifically.

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