Evidence supporting the use of: Xantinol Nicotinate
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Xantinol nicotinate is a vasodilator compound formed from xanthinol and nicotinic acid (niacin). It has been used in clinical settings, particularly in Europe, to improve peripheral and cerebral blood flow. The rationale behind its use to support the capillary system is primarily its pharmacological action as a vasodilator, where it promotes blood flow through the dilation of small blood vessels, including capillaries. Several studies have investigated its effects in conditions involving impaired microcirculation, such as peripheral vascular disease and cerebrovascular insufficiency. The evidence base consists mainly of older clinical trials and publications, many of which report improved microcirculatory parameters and symptomatic relief in patients with vascular disorders. However, high-quality, large-scale randomized controlled trials are limited, and most studies are dated, with few conducted according to modern clinical research standards. There is some support for improved blood flow and capillary function, but the overall strength of the evidence is moderate at best, and it is not widely used in contemporary practice outside specific regions. In summary, there is scientific—though not robust—evidence supporting xantinol nicotinate’s use for capillary and microcirculatory support, meriting a mid-level rating for efficacy.
Other ingredients that support Capillaries
Aescinalpha-glycosyl isoquercitrin
anthocyanidins
anthocyanins
anthocyanosides
apocynin
apple
Aronia melanocarpa
ashitaba
asiaticoside
astragalin
astragalus
baicalein
Baikal Skullcap
benfotiamine
berry
bilberry
bioflavonoids
black currant
blueberry
butcher's broom
capers
capsicum
cayenne pepper
Centella asiatica
Centella triterpenes
Chinese salvia root
chokeberry
Citrus
citrus bioflavonoids
coca
Collinsonia
coumarin
cranesbill
cyanidin
cypress
danshen
delphinidin
dextran
diosmetin
Diosmin
eicosapentaenoic acid
epicatechin
Erigeron
escin
Fagopyrum
fatty acids
fish oil
flavanols
flavanones
flavans
flavoglycosides
flavones
flavonoids
flavonols
flavonones
fruit
garlic bulb
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
gotu kola
grape
Gypenoside
hawthorn
herbal blend (proprietary)
hesperidin
horse chestnut
Hyperoside
Immortelle
Japanese sophora
L-arginine
leucoanthocyanidins
Ligusticum
Ligustrazin
linden
lingzhi
Mineral ascorbate
Nattokinase
Oligomeric proanthocyanidins
onion
orange
pagoda tree
Pentacyclic triterpenoids
Periwinkle
phenolic compounds
Phenylpropanoids
Phosphate ascorbate
pine bark
Polydatin
polymethoxylated flavones
polyphenols
prickly ash
proanthocyanidins
procyanidin
procyanidol
punicalagins
purslane
Pycnogenol
quercetin
rue
Ruscogenins
Ruscus
rutin
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
shepherd's purse
Stone Root
Sweet Clover
Taxifolin
terpene lactones
Terpenoids
Troxerutin
Vincamine
vitamin B
vitamin C
vitamin E
vitamin K
Vitexin
Witch Hazel
Xantinol Nicotinate
Yarrow
Yarrow
Yumberry
