Evidence supporting the use of: Vitamin C (mixed)
For the health condition: Capillary Weakness

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C (ascorbic acid), sometimes provided as "mixed" forms including ascorbate salts, is scientifically recognized for its role in supporting capillary health and addressing capillary weakness. Vitamin C is essential for the biosynthesis of collagen, a structural protein that provides strength and integrity to blood vessel walls, including capillaries. Deficiency in vitamin C results in impaired collagen synthesis, leading to increased capillary fragility, easy bruising, petechiae, and bleeding gums—a constellation of symptoms known as scurvy. Numerous biochemical and clinical studies confirm that adequate vitamin C intake restores normal collagen formation and reduces capillary fragility in individuals with deficiency.

Beyond deficiency states, some studies have investigated vitamin C supplementation for individuals with capillary fragility not caused by overt scurvy, such as in chronic venous insufficiency or certain dermatological conditions. Results suggest that vitamin C, sometimes in combination with bioflavonoids, may modestly reduce capillary bleeding and bruising, though high-quality randomized controlled trials are limited. Nevertheless, the scientific rationale is well-established based on vitamin C’s critical role in collagen stabilization and endothelial function. Thus, the use of vitamin C to support or treat capillary weakness is supported by moderate scientific evidence, particularly in the context of deficiency, and is a standard therapeutic approach in such cases.

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