The use of Heal-All (Prunella vulgaris) for carbuncles is primarily justified by traditional medicine rather than robust scientific validation. In various folk medicinal systems, especially in Europe and Asia, Heal-All has been applied topically or taken internally for a range of skin conditions, including boils, abscesses, and carbuncles. Historical herbal texts often reference its reputed ability to "draw out" infections and promote healing in the case of skin eruptions, which includes carbuncles. The plant contains several bioactive compounds such as rosmarinic acid, flavonoids, and triterpenoids, which possess mild anti-inflammatory and antimicrobial properties when tested in vitro. However, while these properties suggest a plausible mechanism by which Heal-All might support wound healing or reduce infection, there is a lack of direct clinical evidence or controlled studies demonstrating efficacy specifically for carbuncles in humans. The rating of 2 reflects that, while there is a long-standing tradition of use and some preliminary scientific rationale, there is insufficient high-quality evidence to confidently recommend Heal-All as an effective treatment for carbuncles.