The use of "Pussy Ears" (Cyanotis somaliensis or other species colloquially known as "Pussy Ears") for the treatment of carbuncles is primarily supported by traditional medicine rather than robust scientific evidence. In some traditional healing systems, particularly in parts of Asia and Africa, plants with soft, hairy leaves (often called "Pussy Ears") have been applied topically to skin infections, boils, and carbuncles. The rationale behind their use is often based on the perceived soothing, anti-inflammatory, or antimicrobial properties attributed to the plant in folk remedies. However, there is little to no clinical research specifically investigating the efficacy of "Pussy Ears" for carbuncles.

A search of biomedical literature reveals almost no published studies on the direct effects of Cyanotis species (or other plants commonly referred to as "Pussy Ears") on carbuncles or similar skin infections. In some ethnobotanical surveys, these plants are mentioned as part of traditional poultices or topical treatments for a variety of skin issues, but the evidence is anecdotal and not substantiated by controlled studies. The evidence rating is therefore low, as the practice is justified historically and culturally rather than by modern scientific validation.