Evidence supporting the use of: Fiber blend (proprietary)
For the health condition: Cardiovascular Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

A "fiber blend (proprietary)" typically refers to a mixture of soluble and insoluble dietary fibers, commonly including ingredients such as psyllium husk, inulin, oat beta-glucan, and others. Scientific evidence robustly supports the role of dietary fiber in reducing cardiovascular disease (CVD) risk. Multiple large-scale epidemiological studies and clinical trials have demonstrated that higher intakes of dietary fiber are associated with reduced levels of total and LDL cholesterol, lower blood pressure, improved glycemic control, and decreased risk of coronary heart disease and stroke. Soluble fibers like beta-glucan and psyllium are particularly effective at lowering LDL cholesterol, a major risk factor for CVD, by binding bile acids in the gut and increasing their excretion, which forces the liver to use more cholesterol to synthesize new bile acids.

The American Heart Association and European Society of Cardiology recommend increased fiber intake for cardiovascular health. Meta-analyses indicate that each 7-10 grams/day increment in fiber intake is associated with a 9% reduction in risk of coronary heart disease events. However, the exact efficacy of a "proprietary" blend depends on its specific composition, which is often undisclosed. While the general use of dietary fiber for cardiovascular health is scientifically validated, the evidence rating is not maximal (5) due to variability in fiber formulations and possible lack of transparency about ingredient proportions in proprietary blends.

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Other ingredients used for Cardiovascular Disease

coenzyme Q10 (CoQ10)
curcumin
fiber blend (proprietary)
green tea
magnesium
omega-3 fatty acids
selenium
zinc
7-hydroxymatairesinol (HMR)
Acacetin
acai berry
Acer Truncatum bunge
acetyl l-carnitine
Acetylsalicylic acid
algal oil
Algal protein
Allicin
almond fruit
Alpha phytosterol
alpha-carotene
alpha-linolenic acid (ALA)
amaranth
AMP-activated protein kinase (AMPK)
Ampelopsin
anchovies
Animal Tissue
anthocyanidins
anthocyanins
anthocyanosides
Antirrhinin
Apigenin
Apocynin
Argan nut oil
Adrenergic amines
ajoene
Alliin
Alpha-Lipoic Acid
apple
Arginine Creatine
Arginine nitrate
arjun tree
Arjuna
Arjunic Acid
Arjunolic acid
Aronia melanocarpa
astaxanthin
Asteracea
Astragalin
Astragaloside
Avocado
Baicalin
Basidiomycota
basil
Bee products
beet
Benfotiamine
berry
berry flavor
Beta-hydroxybutyrate
Betanin
Bidens pilosa
bilberry
Bioflavonoids
black garlic
black tea
blackberry
blueberry
bonito peptide
Brassica
Alcohol
algae
amino acids
Ardisia
Arginine silicate
astragalus
banana
Bassia scoparia
Bishop's Weed
black ginger
Black Seed
broccoli
calamari oil
campesterol
canola oil
capsaicinoids
capsicum
Cashew
catechins
caterpillar mushroom
cayenne pepper
chia seed
chokeberry
choline
chrysanthemum
cinnamon
cistanche
citrus bioflavonoids
citrus sinensis (proprietary)
cocoa
commiphora
conjugated linoleic acid (CLA)
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethanol
ferulic acid
fisetin
fish oil
fish protein
flavonols
flaxseed
folate
fruit and vegetable blend (proprietary)
gamma tocopherol
ganoderma
Garlic
garlic bulb
gastrodia
genistein
ginger
ginseng
goji berry
grape
greens blend (proprietary)
hawthorn
herbal blend (proprietary)
hesperetin
hesperidin
HMR lignan
jiaogulan
krill oil
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glycine
l-taurine
lactobacillus reuteri
lignans
linoleic acid (LA)
luteolin
lycopene
mackerel
marine lipid
matcha
millet seed
motherwort
mustard seed
n-acetyl-cysteine (NAC)
nattokinase
nicotinamide riboside
oleic acid
olive
omega-6 fatty acids
omega-9 fatty acids
onion
orange
palmitoleic acid
pantethine
peanut
phenolic acids
phospholipids
phytosterols
pine bark
pineapple
plant sterols
policosanol
pollen
polyphenols
pomegranate
potassium
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
raspberry
red clover
red yeast rice
reishi mushroom
resveratrol
rhizome
royal jelly
rutin
sardines
secoisolariciresinol diglucoside
sitostanol
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
spinach
sterols
strawberry
sulforaphane glucosinolate
tocotrienols
tomato
trace minerals
trans-pterostilbene
trimethylglycine (TMG)
triphala
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
vitamin K
walnut
watermelon
yerba mate
Zucchini
β-nicotinamide mononucleotide (NMN)