Evidence supporting the use of: Terpene Lactone (unspecified)
For the health condition: Cardiovascular Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Terpene lactones, most notably ginkgolides and bilobalide from Ginkgo biloba extract, have been studied for their effects on cardiovascular health. The primary rationale for their use is based on their ability to inhibit platelet-activating factor (PAF), reduce blood viscosity, and improve microcirculation. These mechanisms are thought to help prevent thrombosis and improve blood flow, which could be beneficial in cardiovascular diseases such as peripheral artery disease and, to a lesser extent, in protecting against ischemic events.

Several clinical trials and meta-analyses have evaluated Ginkgo biloba extract (which contains terpene lactones alongside flavonoids) in cardiovascular and cerebrovascular conditions. The evidence suggests mild to modest benefits, particularly in improving symptoms of intermittent claudication (a manifestation of peripheral artery disease). However, robust evidence for the prevention or treatment of major cardiovascular events (e.g., heart attack, stroke) remains lacking. Most guidelines do not recommend terpene lactones as standard therapy for cardiovascular diseases, and any benefits observed tend to be adjunctive rather than primary.

Overall, while there is some scientific basis and clinical research supporting the use of terpene lactone-containing extracts for certain circulatory conditions, the overall strength of evidence is limited (rated 2 out of 5). Their use should not replace established treatments, and more rigorous studies are needed to define their role in cardiovascular disease management.

More about Terpene Lactone (unspecified)
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Products containing Terpene Lactone (unspecified)

We currently have no products on Vitabase that contain this ingredient.