Relationship: Carpal Tunnel Syndrome and selenium

Evidence supporting the use of: Selenium
For the health condition: Carpal Tunnel Syndrome

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Source of validity: Scientific
Rating (out of 5): 2

Synopsis: Selenium has been investigated for its potential role in treating Carpal Tunnel Syndrome (CTS) based on its antioxidant properties. Oxidative stress and inflammation are believed to contribute to the pathophysiology of CTS, and selenium is an essential trace element that acts as a cofactor for antioxidant enzymes such as glutathione peroxidase. A few clinical studies, mainly from Europe, have explored the use of selenium supplementation in CTS patients. Notably, a randomized controlled trial published in 2011 (Seelig et al.) demonstrated that oral selenium supplementation (200 mcg/day) for several weeks led to a statistically significant reduction in CTS symptoms compared to placebo. The proposed mechanism is the reduction of oxidative stress and modulation of inflammatory pathways, which could theoretically decrease nerve irritation within the carpal tunnel.

However, these studies are relatively small and not widely replicated, and some have methodological limitations. There are no large-scale, high-quality randomized controlled trials establishing selenium as a standard therapy for CTS. Major clinical guidelines do not currently recommend selenium for this indication. Thus, while there is some scientific basis and preliminary clinical evidence, the overall strength of evidence is low to moderate, and more research is needed to confirm efficacy and safety. Selenium supplementation should not replace established therapies such as wrist splinting, corticosteroid injections, or surgery in moderate to severe cases of CTS.

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rosemary
selenium
vitamin B12
vitamin B6

Other health conditions supported by selenium

Acquired Immune Deficiency Syndrome
Aging (prevention)
Alzheimer's Disease
Arrhythmia
Athlete's Foot
Autoimmune Disorders
Bell's Palsy
Blood Poisoning
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Carpal Tunnel Syndrome
Cervical Dysplasia
Chemical Poisoning
Chemotherapy (reducing side effects)
Cirrhosis of the Liver
Dementia
Depression
Eye Problems
Free Radical Damage
Goiter
Grave's Disease
Hair (loss or thinning)
Hepatitis
Infection
Infection (viral)
Inflammation
Influenza
Liver Detoxification
Memory and Brain Function

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Evidence supporting the use of: Selenium
For the health condition: Carpal Tunnel Syndrome

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Synopsis

Other ingredients used for Carpal Tunnel Syndrome

Health Concerns

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Evidence supporting the use of: SeleniumFor the health condition: Carpal Tunnel Syndrome

Table of Contents

Synopsis

Other ingredients used for Carpal Tunnel Syndrome

Other health conditions supported by selenium

Products containing selenium

Evidence supporting the use of: Selenium
For the health condition: Carpal Tunnel Syndrome