Evidence supporting the use of: Vitamin B6 (various)
For the health condition: Carpal Tunnel Syndrome
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Vitamin B6 (pyridoxine) has been used traditionally to support or treat Carpal Tunnel Syndrome (CTS), especially since the 1970s. Early observational studies and anecdotal reports suggested that vitamin B6 supplementation might alleviate symptoms in some individuals, particularly those with low B6 status. Several small, uncontrolled studies or case series found improvements in nerve conduction and symptom relief among CTS patients given high doses of vitamin B6. However, subsequent randomized controlled trials (RCTs) have largely failed to demonstrate a significant benefit of vitamin B6 supplementation compared to placebo in the general CTS population, especially in those without clear deficiency. Systematic reviews and clinical guidelines generally do not recommend vitamin B6 as a standard therapy for CTS, citing insufficient evidence. Despite this, the use persists in some alternative medicine and nutritional circles, rooted more in historical practice than in robust scientific validation. Current consensus is that vitamin B6 supplementation may be considered only in cases of documented deficiency, and not as a general treatment for CTS. In summary, the use of vitamin B6 for CTS is primarily based on tradition, with limited and inconsistent scientific evidence supporting its efficacy.
More about Vitamin B6 (various)
More about Carpal Tunnel Syndrome
Other health conditions supported by Vitamin B6 (various)
AnemiaAnxiety
Anxiety Disorders
Appetite (deficient)
Anger (excessive)
Attention Deficit Disorder
Autism
Burning Feet or Hands
Cancer Treatment (reducing side effects)
Carpal Tunnel Syndrome
Cramps (menstrual)
Depression
Diabetes
Dysmenorrhea
Emotional Sensitivity
Epilepsy
Fatigue