Evidence supporting the use of: Glucosamine potassium sulfate
For the health condition: Cartilage Damage

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glucosamine potassium sulfate is commonly used as a dietary supplement to support joint health and potentially treat cartilage damage, particularly in conditions like osteoarthritis. Scientific interest in glucosamine arises from its role as a precursor for glycosaminoglycans, which are key components of cartilage. Some clinical trials and meta-analyses have evaluated the efficacy of glucosamine (usually as sulfate or hydrochloride salts) for reducing joint pain and slowing cartilage degradation.

However, the scientific evidence supporting its effectiveness is mixed. Several studies, including large randomized controlled trials, have found little or no clinically meaningful benefit over placebo in reducing pain or improving function in patients with cartilage damage or osteoarthritis. Some smaller studies and subgroup analyses have suggested modest benefits, but these findings have not been consistently replicated. The 2019 guidelines from the American College of Rheumatology and other major organizations generally do not recommend glucosamine for osteoarthritis due to insufficient evidence of efficacy.

It is important to note that most research has focused on glucosamine sulfate or hydrochloride, and there is limited specific data on the potassium sulfate salt. Overall, while the use of glucosamine for cartilage damage is based on plausible biological mechanisms and some positive findings, the totality of scientific evidence does not strongly support its effectiveness, justifying a low evidence rating.

More about Glucosamine potassium sulfate
More about Cartilage Damage

Other health conditions supported by Glucosamine potassium sulfate

Arthritis
Cartilage Damage

Products containing Glucosamine potassium sulfate

We currently have no products on Vitabase that contain this ingredient.