Evidence supporting the use of: Vitamin B2 (riboflavin selenite)
For the health condition: Cataracts
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin B2, also known as riboflavin, has some scientific rationale for its use in cataract prevention and support, although the evidence is not robust. Riboflavin is an essential nutrient involved in cellular energy production and the maintenance of normal vision. Oxidative stress is a key factor in the development of cataracts, and riboflavin acts as a cofactor for glutathione reductase, an enzyme important in protecting the lens from oxidative damage. Several observational studies have found associations between low dietary intake of riboflavin and an increased risk of cataracts. For example, population-based studies have reported that higher riboflavin intake correlates with a lower incidence of age-related cataracts. However, intervention trials supplementing riboflavin specifically for cataract prevention are limited and have not consistently demonstrated a clear benefit. Riboflavin deficiency is known to cause ocular symptoms, including cataracts in severe cases, supporting the idea that adequate levels are important for lens health. It is important to note that "riboflavin selenite" is not a standard form of riboflavin used in clinical practice or research; therapeutic use typically involves riboflavin (as riboflavin or riboflavin-5-phosphate). In summary, while there is a plausible biological mechanism and some supportive epidemiological evidence, high-quality clinical trials are lacking, and the evidence supporting riboflavin supplementation specifically for cataract prevention or treatment is limited.
More about Vitamin B2 (riboflavin selenite)
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Other health conditions supported by Vitamin B2 (riboflavin selenite)
CataractsDermatitis
Fatigue
Headache (general)
Headache (tension)
Migraine