Evidence supporting the use of: Alkylglycerols
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Alkylglycerols (AKGs), naturally occurring ether lipids found in high concentrations in shark liver oil and human bone marrow, have been explored for their potential to support cancer patients undergoing chemotherapy, particularly in mitigating certain side effects. The interest in AKGs originated from observations that populations consuming shark liver oil experienced better resistance to infections and improved healing, which led to scientific investigations in the 20th century. Some preclinical and small clinical studies have suggested that AKGs may enhance hematopoiesis (the formation of blood cells), support immune function, and potentially reduce leukopenia (a reduction in white blood cell count) caused by chemotherapy. For instance, a few studies from the 1990s and early 2000s reported that AKG supplementation led to improved white blood cell counts and shorter durations of neutropenia in cancer patients receiving cytotoxic therapy. The proposed mechanisms include stimulation of macrophage and granulocyte activity as well as modulation of cytokine production. However, the overall quality and size of these studies are limited, with few randomized controlled trials and inconsistent methodologies. Larger, well-controlled clinical trials are lacking, and thus the evidence for AKGs’ effectiveness in reducing chemotherapy side effects remains preliminary and not widely endorsed by mainstream oncology guidelines. In summary, while there is some scientific basis for their use, current evidence is limited, inconsistent, and insufficient for strong recommendations.
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Other ingredients used for Chemotherapy (reducing side effects)
aloe veraalpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe
Other health conditions supported by Alkylglycerols
Cancer (natural therapy for)Chemotherapy (reducing side effects)
Convalescence
Infection
Infection (viral)
Radiation Sickness
Wounds and Sores