Evidence supporting the use of: Alpha lactalbumin
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Alpha-lactalbumin, a major whey protein found in milk, has attracted research interest for its potential benefits during chemotherapy, particularly in reducing side effects and supporting immune function. The scientific basis for its use centers around its high tryptophan content and its ability to form complexes (such as HAMLET—Human Alpha-lactalbumin Made LEthal to Tumor cells) that may selectively induce apoptosis in tumor cells while sparing healthy cells. Some in vitro and animal studies have shown that HAMLET can kill cancer cells and may enhance the efficacy of chemotherapy, possibly reducing required doses and associated toxicity.
Additionally, alpha-lactalbumin is a rich source of essential amino acids and bioactive peptides, which may help support immune function and improve nutritional status in patients undergoing chemotherapy, who are at risk for malnutrition and immunosuppression.
However, clinical evidence in humans is limited. Most studies have been preclinical or conducted in small cohorts, and robust, placebo-controlled clinical trials specifically evaluating alpha-lactalbumin for mitigating chemotherapy side effects are lacking. While the mechanistic rationale is promising and animal data are supportive, more research is needed to establish efficacy and safety in cancer patients. Therefore, scientific evidence exists but is currently limited, justifying a moderate-low evidence rating.
More about Alpha lactalbumin
More about Chemotherapy (reducing side effects)
Other ingredients used for Chemotherapy (reducing side effects)
aloe veraalpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe
Other health conditions supported by Alpha lactalbumin
AnxietyChemotherapy (reducing side effects)
Depression
Diabetes
Fatigue
Inflammation
Insomnia
Nervousness
Stress