Evidence supporting the use of: Antioxidant (unspecified)
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Antioxidants have been explored as adjuncts to chemotherapy primarily to reduce the side effects caused by oxidative stress induced by many chemotherapeutic agents. Scientific interest in this area stems from the fact that chemotherapy drugs, such as doxorubicin and cisplatin, generate reactive oxygen species (ROS) as part of their mechanism of action, which can lead to collateral damage in healthy tissues. This has prompted investigations into whether antioxidants (such as vitamin E, vitamin C, selenium, and N-acetylcysteine) might mitigate these toxicities without reducing the effectiveness of chemotherapy. However, the evidence supporting the use of unspecified antioxidants for reducing chemotherapy side effects is mixed and somewhat controversial. Some clinical trials and systematic reviews suggest modest benefits in terms of reducing specific side effects (e.g., neuropathy, mucositis, cardiotoxicity), but others have raised concerns that antioxidants could also protect cancer cells from oxidative damage, potentially reducing chemotherapy efficacy. Meta-analyses and clinical guidelines emphasize caution, as the heterogeneity of studies, the use of different antioxidants, dosages, and timing, as well as the lack of large, high-quality randomized controlled trials, limit firm conclusions. Overall, there is some scientific basis for using antioxidants to reduce chemotherapy side effects, but evidence is inconsistent and not robust enough to universally recommend their use. Most oncologists advise against routine antioxidant supplementation during chemotherapy outside of clinical trials.

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Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe

Products containing Antioxidant (unspecified)

We currently have no products on Vitabase that contain this ingredient.