Evidence supporting the use of: Astaxanthin
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Astaxanthin is a potent antioxidant carotenoid found in microalgae, yeast, salmon, and other seafood. Its use in the context of chemotherapy is primarily supported by preclinical and limited clinical evidence. Chemotherapy often causes significant oxidative stress and inflammation, leading to side effects such as fatigue, organ toxicity, and damage to healthy tissues. Astaxanthin's antioxidant properties may help counteract these effects by scavenging reactive oxygen species (ROS) and reducing oxidative damage. Several animal studies have demonstrated that astaxanthin can protect cells from chemotherapy-induced toxicity, such as cardiotoxicity associated with doxorubicin. Additionally, some in vitro studies suggest that astaxanthin can modulate immune responses and reduce inflammation, which may further support its potential to alleviate chemotherapy side effects.

However, human clinical data are sparse. A few small-scale trials and observational studies have reported improvements in markers of oxidative stress and inflammation in cancer patients taking astaxanthin, but robust, large-scale randomized controlled trials are lacking. Therefore, while there is a plausible scientific rationale and promising preliminary data, the overall strength of evidence is limited, and more research is needed to validate astaxanthin's efficacy in reducing chemotherapy side effects. Patients considering astaxanthin should consult their oncologist, as interactions with chemotherapy drugs have not been fully elucidated.

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Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
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Clostridium butyricum
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Ergothioneine
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