Evidence supporting the use of: Boronic acid analogues
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Boronic acid analogues are not broadly used to support or reduce the side effects of chemotherapy in a general sense, but rather have a specific, scientifically validated role as chemotherapeutic agents themselves, most notably in the treatment of multiple myeloma. The prototypical boronic acid analogue, bortezomib, is a proteasome inhibitor that induces apoptosis in cancer cells by disrupting protein degradation pathways. Its use is based on robust preclinical and clinical trial data. However, the characterization of boronic acid analogues as "supportive" agents to reduce the side effects of other chemotherapies is not supported by the current scientific literature. Instead, bortezomib and similar compounds are used as primary anti-cancer therapies rather than adjuncts for side effect management.
Some research explores the potential of boronic acid compounds to act as enzyme inhibitors or antioxidants, which could theoretically have supportive roles, but these applications remain investigational and have not entered routine clinical practice. Therefore, the main scientific validation for boronic acid analogues relates to their direct anti-cancer effects, not the mitigation of chemotherapy-induced side effects.
In summary, there is a scientific basis for using boronic acid analogues in cancer therapy, but not specifically for reducing chemotherapy side effects, and the evidence for such supportive use is limited to theoretical or early-stage research.
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Other ingredients used for Chemotherapy (reducing side effects)
aloe veraalpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
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coenzyme Q10 (CoQ10)
colostrum
turmeric
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cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
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l-glycine
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lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
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AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
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Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
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benzyl isothiocyanate
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C-Phycocyanin
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Other health conditions supported by Boronic acid analogues
Antibiotics (alternatives to)Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Diabetes
Infection (bacterial)
Inflammation