Evidence supporting the use of: Cannabidiol
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cannabidiol (CBD), a non-psychoactive compound found in cannabis, has garnered significant interest for its potential to alleviate certain side effects of chemotherapy, such as nausea, vomiting, pain, and anxiety. Scientific evidence for CBD’s efficacy in this context is moderate and still emerging. The strongest evidence relates to the broader use of cannabinoids (including THC and CBD) for chemotherapy-induced nausea and vomiting (CINV). While synthetic THC analogs (like dronabinol and nabilone) have been approved for this purpose, CBD itself has not been broadly approved or as extensively studied in randomized controlled trials for CINV.

Some studies and preclinical models suggest that CBD, alone or in combination with THC, may help reduce nausea, stimulate appetite, and manage chronic pain and inflammation—common side effects of chemotherapy. Additionally, CBD’s anxiolytic properties may help reduce anxiety in cancer patients. However, most clinical studies have used whole-plant cannabis or combinations of THC and CBD, making it difficult to isolate the effects of CBD specifically.

Major cancer and palliative care guidelines acknowledge the potential of cannabinoids in supportive care but generally stop short of recommending CBD alone due to limited high-quality clinical evidence. More robust, well-designed clinical trials are needed to determine optimal dosing, efficacy, and safety of CBD for chemotherapy-related side effects. Thus, while there is a scientific rationale and some supportive evidence, its routine use for this indication is not yet fully validated.

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Other ingredients used for Chemotherapy (reducing side effects)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Acemannan
AHCC
Alkylglycerols
Aloe vera
Alpha Glucans
Alpha lactalbumin
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amino acids
anthocyanins
Antrodia camphorata
astaxanthin
astragalus
Baikal Skullcap
BCAA
benzyl isothiocyanate
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
black cumin
black currant
blueberry
Boswellic Acid
branched-chain amino acids
bromelain
C-phycocyanin
cannabidiol
cannabigerol
Cannabis sativa oil
caryophyllene
chamomile
chlorella
Clostridium butyricum
Codonopsis
coenzyme Q10 (CoQ10)
coix
colostrum
curcumin
Curcuminoid
cyclodextrin
d-alpha tocopherol
dithiolthiones
ergothioneine
fish oil
folinic acid
fucoidan
ginger
Glutamine
Glutathione
grape
green tea
Haematococcus pluvialis
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
HMB hydroxymethylbutyrate
Honokiol
hydroxymethylbutyrate
Hyphomycetes
L-alanyl-L-glutamine
L-carnosine
L-cysteine
L-glutamine
L-glutathione
L-glycine
L-taurine
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus lactis
Lactobacillus plantarum
Lactoferrin
lactoglobulin
Lentinan
Lentinula edodes mycelia
licorice root
lion's mane
luteolin
Marine lipid
Matcha
Melatonin
Mesima
Methylselenocysteine
Milk Protein
Milk thistle
Mistletoe
Mushroom
N-acetyl-cysteine (NAC)
Oldenlandia diffusa
Palmitoylethanolamide (PEA)
Peptides
Phenethyl isothiocyanate (PEITC)
phytocannabinoids
polysaccharides
pomegranate
probiotics
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
Saccharomyces boulardii
Saccharomyces cerevisiae
selenium
Selenomethionine
shiitake mushroom
Silychristin
soy isoflavones
spirulina
streptococcus thermophilus
Sulforaphane
Thymidine
Thymoquinone
tributyrin
Turkey tail mushroom
turmeric
Typhonium flagelliforme
Verbascoside
vitamin B6
vitamin C
vitamin E
Whey protein
Zinc

Products containing cannabidiol

We currently have no products on Vitabase that contain this ingredient.