Evidence supporting the use of: Curcuminoid
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcuminoids, the active compounds found in turmeric (Curcuma longa), have been studied for their potential to reduce the side effects of chemotherapy, primarily due to their anti-inflammatory, antioxidant, and cytoprotective properties. Several preclinical studies and some clinical trials suggest that curcuminoids may mitigate certain chemotherapy-induced toxicities, such as mucositis, neuropathy, and organ damage. For example, randomized controlled trials have shown that curcumin supplementation can reduce the severity and incidence of oral mucositis in patients undergoing chemotherapy and radiotherapy for head and neck cancers. Additionally, animal studies report protective effects of curcumin against chemotherapy-induced nephrotoxicity, hepatotoxicity, and neurotoxicity. The proposed mechanisms include modulation of inflammatory pathways (e.g., NF-κB inhibition), scavenging of reactive oxygen species, and upregulation of cellular defense enzymes. However, despite these promising results, the overall evidence is still considered moderate (rated 3/5). Many studies are small, heterogeneous, or preclinical, and issues with curcumin’s bioavailability limit its clinical translation. Larger, well-designed clinical trials are needed to confirm efficacy and safety, as well as to determine optimal dosing and formulations. Nonetheless, current data do provide a scientific basis for the cautious use of curcuminoids to support patients undergoing chemotherapy, especially to alleviate some side effects, though they should not replace conventional supportive care.

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Other ingredients used for Chemotherapy (reducing side effects)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Acemannan
AHCC
Alkylglycerols
Aloe vera
Alpha Glucans
Alpha lactalbumin
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amino acids
anthocyanins
Antrodia camphorata
astaxanthin
astragalus
Baikal Skullcap
BCAA
benzyl isothiocyanate
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
black cumin
black currant
blueberry
Boswellic Acid
branched-chain amino acids
bromelain
C-phycocyanin
cannabidiol
cannabigerol
Cannabis sativa oil
caryophyllene
chamomile
chlorella
Clostridium butyricum
Codonopsis
coenzyme Q10 (CoQ10)
coix
colostrum
curcumin
Curcuminoid
cyclodextrin
d-alpha tocopherol
dithiolthiones
ergothioneine
fish oil
folinic acid
fucoidan
ginger
Glutamine
Glutathione
grape
green tea
Haematococcus pluvialis
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
HMB hydroxymethylbutyrate
Honokiol
hydroxymethylbutyrate
Hyphomycetes
L-alanyl-L-glutamine
L-carnosine
L-cysteine
L-glutamine
L-glutathione
L-glycine
L-taurine
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus lactis
Lactobacillus plantarum
Lactoferrin
lactoglobulin
Lentinan
Lentinula edodes mycelia
licorice root
lion's mane
luteolin
Marine lipid
Matcha
Melatonin
Mesima
Methylselenocysteine
Milk Protein
Milk thistle
Mistletoe
Mushroom
N-acetyl-cysteine (NAC)
Oldenlandia diffusa
Palmitoylethanolamide (PEA)
Peptides
Phenethyl isothiocyanate (PEITC)
phytocannabinoids
polysaccharides
pomegranate
probiotics
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
Saccharomyces boulardii
Saccharomyces cerevisiae
selenium
Selenomethionine
shiitake mushroom
Silychristin
soy isoflavones
spirulina
streptococcus thermophilus
Sulforaphane
Thymidine
Thymoquinone
tributyrin
Turkey tail mushroom
turmeric
Typhonium flagelliforme
Verbascoside
vitamin B6
vitamin C
vitamin E
Whey protein
Zinc

Products containing Curcuminoid

We currently have no products on Vitabase that contain this ingredient.