Evidence supporting the use of: Echinacosides
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Echinacoside is a natural phenylethanoid glycoside primarily found in Echinacea species and other medicinal plants like Cistanche tubulosa. There is some preliminary scientific evidence suggesting that echinacoside may help reduce certain chemotherapy-induced side effects, primarily through its antioxidant, anti-inflammatory, and neuroprotective properties. Animal studies and in vitro experiments have shown that echinacoside can mitigate oxidative stress, decrease inflammation, and protect neuronal cells from damage. These properties are theoretically beneficial in the context of chemotherapy, which often induces oxidative damage and inflammation, contributing to side effects such as neurotoxicity and organ injury.
A few preclinical studies have specifically examined echinacoside's ability to ameliorate chemotherapy-induced neurotoxicity and nephrotoxicity. For example, research on rats has demonstrated that echinacoside supplementation can reduce cisplatin-induced kidney damage by attenuating oxidative stress and apoptosis. Similarly, other studies have indicated its protective effect against nerve damage caused by chemotherapeutic agents. However, there are currently no large-scale clinical trials in humans directly evaluating echinacoside for the reduction of chemotherapy side effects.
In summary, while laboratory and animal studies provide some scientific basis for echinacoside's potential to support chemotherapy patients by reducing certain side effects, the evidence is still limited and primarily preclinical. High-quality human studies are needed before echinacoside can be recommended for this use with confidence.
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alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
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l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
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pectin
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pomegranate
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quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
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tributyrin
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vitamin B6
vitamin C
vitamin E
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zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
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AHCC
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Other health conditions supported by Echinacosides
Chemotherapy (reducing side effects)Infection
Infection (bacterial)
Infection (viral)
Inflammation