Relationship: Chemotherapy (reducing side effects) and grape

Evidence supporting the use of: Grape
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Grapes, particularly their skins and seeds, are rich in polyphenolic compounds such as resveratrol, quercetin, and proanthocyanidins, which have been studied for their antioxidant and anti-inflammatory properties. Some scientific studies have explored the potential of grape-derived products to mitigate the side effects of chemotherapy, including oxidative stress, mucositis, and organ toxicity. For example, animal studies have shown that grape seed extract and resveratrol may reduce chemotherapy-induced damage to organs such as the liver and kidneys, likely due to their ability to scavenge free radicals and modulate inflammatory pathways. There is also preliminary evidence in laboratory and animal models that resveratrol could protect healthy cells from some of the collateral damage caused by chemotherapy agents.

However, high-quality clinical trials in humans are limited. Some small-scale studies have suggested that oral supplementation with grape seed extract or resveratrol might reduce chemotherapy-induced mucositis or fatigue, but results are not consistent, and concerns remain regarding possible interactions between these supplements and chemotherapy drugs. For instance, resveratrol may influence the metabolism of certain chemotherapeutic agents, potentially altering their efficacy.

In summary, while there is a scientific rationale and some supportive preclinical data for the use of grape-derived products in reducing chemotherapy side effects, current clinical evidence is not robust enough to make definitive recommendations. Thus, the evidence supporting its use is rated as 2 out of 5.

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Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe

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Evidence supporting the use of: Grape
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Other ingredients used for Chemotherapy (reducing side effects)

Other health conditions supported by grape

Products containing grape

Health Concerns

Brands

Evidence supporting the use of: GrapeFor the health condition: Chemotherapy (reducing side effects)

Table of Contents

Synopsis

Other ingredients used for Chemotherapy (reducing side effects)

Other health conditions supported by grape

Products containing grape

Evidence supporting the use of: Grape
For the health condition: Chemotherapy (reducing side effects)