Evidence supporting the use of: Lactobacillus mixed)
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Lactobacillus (usually in mixed probiotic formulations) has been studied for its potential to reduce certain side effects of chemotherapy, particularly gastrointestinal issues like diarrhea and mucositis. Chemotherapy can disrupt the normal balance of gut microbiota, which may contribute to these side effects. Several randomized controlled trials and meta-analyses have explored whether supplementation with probiotics containing Lactobacillus strains can prevent or lessen chemotherapy-induced diarrhea, especially in patients with colorectal or pelvic cancers.
Evidence suggests that probiotics, including Lactobacillus species, can reduce the incidence and severity of diarrhea in some chemotherapy regimens. For example, a 2018 meta-analysis in Supportive Care in Cancer found a statistically significant reduction in chemotherapy-associated diarrhea with probiotic supplementation. Some studies also report benefits in reducing the severity of oral mucositis.
However, the strength of evidence is moderate (rated 3/5), as studies are often small, use different probiotic combinations, and vary in patient populations and chemotherapy types. While the majority of data is positive, there is still no universal consensus on the most effective strains, doses, or treatment durations. Probiotics are generally considered safe in immunocompetent patients, but caution is advised in severely immunocompromised individuals.
In summary, there is scientific evidence (though not definitive) supporting the use of mixed Lactobacillus probiotics to help reduce certain chemotherapy side effects, mainly gastrointestinal symptoms.
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Other ingredients used for Chemotherapy (reducing side effects)
aloe veraalpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe
Other health conditions supported by Lactobacillus mixed)
Acid IndigestionAllergies (food)
Allergies (respiratory)
Antibiotics (alternatives to)
Antibiotics (side effects of)
Anxiety
Anxiety Disorders
Bladder Infection
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Cholesterol (high)
Colitis
Constipation (adults)
Constipation (children)
Crohn's Disease
Diarrhea
Digestion (poor)
Diverticulitis
Dyspepsia
Eczema
Gastritis
Gingivitis
Halitosis
Infection
Infection (bacterial)
Inflammation
Inflammatory Bowel Disorders
Irritable Bowel Syndrome