Evidence supporting the use of: Marine lipid
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Marine lipids, particularly omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been investigated for their role in reducing chemotherapy-induced side effects. Scientific interest in these compounds centers on their anti-inflammatory properties and their potential to modulate immune function, which may help alleviate symptoms like cachexia (muscle wasting), neuropathy, and general inflammation observed during chemotherapy.

A number of clinical studies and meta-analyses suggest that supplementation with marine lipids can help maintain or improve body weight, muscle mass, and quality of life in cancer patients undergoing chemotherapy. For example, a meta-analysis published in Cancer Treatment Reviews (2017) concluded that omega-3 supplementation was associated with improved nutritional status and reduced inflammatory markers in cancer patients. Additional clinical trials have indicated that omega-3 PUFAs may reduce the severity of chemotherapy-induced peripheral neuropathy and support immune function.

Despite these promising findings, the quality and size of available studies are variable, and some have shown only modest or inconsistent benefits. The optimal dosage, duration, and formulation of marine lipid supplementation have not been standardized. As such, while there is a moderate level of scientific evidence supporting the use of marine lipids to help mitigate certain chemotherapy side effects, more large-scale, well-controlled studies are needed to establish definitive recommendations.

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