Evidence supporting the use of: Phytocannabinoid (unspecified)
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Phytocannabinoids, particularly those derived from cannabis such as delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), have scientific support for use in reducing certain side effects of chemotherapy. The most well-documented benefits are for chemotherapy-induced nausea and vomiting (CINV). Several randomized controlled trials and systematic reviews have shown that cannabinoid-based medications (such as dronabinol and nabilone, both synthetic cannabinoids) are effective antiemetics. These studies have led to the approval of cannabinoid drugs by regulatory bodies like the FDA for the management of CINV in patients who do not respond to standard therapy.
There is also emerging, though less robust, evidence that phytocannabinoids may help with other chemotherapy side effects such as pain, appetite loss, and sleep disturbances. However, for these indications, data are less consistent and often limited to small studies or observational reports. The main risks associated with phytocannabinoid use include psychoactive effects (primarily with THC), potential drug interactions, and variability in individual response.
Guidelines from organizations such as the American Society of Clinical Oncology recognize cannabinoids as an option for patients experiencing refractory CINV. While not considered first-line therapy, phytocannabinoids are a validated adjunct for patients who do not achieve relief with more established antiemetic regimens.
More about Phytocannabinoid (unspecified)
More about Chemotherapy (reducing side effects)
Other ingredients used for Chemotherapy (reducing side effects)
aloe veraalpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe
Other health conditions supported by Phytocannabinoid (unspecified)
Abdominal PainAcquired Immune Deficiency Syndrome
Addictions (drugs)
Addictions (general remedies for)
Alzheimer's Disease
Anxiety
Anxiety Disorders
Appetite (deficient)
Arthritis
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Depression
Diabetes
Dysmenorrhea
Epilepsy
Glaucoma
Inflammation
Insomnia
Migraine
Multiple Sclerosis
Muscle Tone (lack of)
Nausea and Vomiting
Neuralgia and Neuritis
Pain (general remedies for)
Parkinson's Disease
Post Traumatic Stress Disorder