Evidence supporting the use of: Pomegranate
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Pomegranate (Punica granatum) has gained interest as a supportive therapy during chemotherapy, primarily due to its rich polyphenol content and strong antioxidant properties. Several preclinical studies and a small number of clinical trials suggest that pomegranate juice or extracts may help mitigate some chemotherapy-induced side effects, particularly oxidative stress and inflammation. For example, animal models have shown that pomegranate can reduce chemotherapy-induced nephrotoxicity and hepatotoxicity, likely by decreasing oxidative damage and modulating inflammatory pathways.

Some small human studies have looked at pomegranate’s role in reducing chemotherapy-associated oral mucositis and fatigue, reporting mild beneficial effects. The proposed mechanisms involve scavenging free radicals, reducing lipid peroxidation, and supporting endogenous antioxidant enzyme systems. However, comprehensive, large-scale randomized controlled trials in cancer patients are lacking, and the evidence base is still emerging.

While pomegranate has not been a part of traditional chemotherapy support (since chemotherapy is a modern intervention), it has a long history of use in traditional medicine for general health and as a tonic. Its current use alongside chemotherapy is primarily based on scientific rationale and preliminary data, rather than traditional precedent.

Overall, while there is a modest but growing body of scientific evidence supporting the use of pomegranate to reduce certain chemotherapy side effects, more robust clinical trials are needed before it can be strongly recommended.

More about pomegranate
More about Chemotherapy (reducing side effects)

Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe

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Metagenics Wellness Essentials Active Daily Packs
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