Evidence supporting the use of: Tetrahydrocannabinol
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Tetrahydrocannabinol (THC), the principal psychoactive component of cannabis, has been scientifically validated for its use in alleviating certain chemotherapy-induced side effects, most notably nausea and vomiting. Multiple randomized controlled trials and meta-analyses have demonstrated that synthetic THC analogues such as dronabinol and nabilone are effective antiemetics in patients undergoing chemotherapy, especially in cases where conventional therapies have failed. These findings have led to the approval of these agents by regulatory bodies such as the U.S. Food and Drug Administration (FDA) for the management of chemotherapy-induced nausea and vomiting (CINV). The efficacy of THC is thought to be mediated through interaction with the endocannabinoid system, particularly CB1 receptors in the central nervous system, which help modulate emetic responses.

While THC-based medications can cause side effects such as dizziness, dysphoria, and euphoria, their benefit in refractory cases has been consistently observed. In addition to antiemetic effects, there is some clinical evidence suggesting that THC may help stimulate appetite in cancer patients experiencing cachexia, though this use is less well-established. Overall, the scientific evidence supporting the use of THC for chemotherapy-induced nausea and vomiting is robust, meriting a rating of 4 out of 5, primarily due to consistent clinical trial data, regulatory approval, and inclusion in treatment guidelines as an option for patients unresponsive to first-line antiemetics.

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More about Chemotherapy (reducing side effects)

Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe

Products containing Tetrahydrocannabinol

We currently have no products on Vitabase that contain this ingredient.