Evidence supporting the use of: Vitamin E (gamma unspecified)
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, including the gamma-tocopherol form, has been studied for its potential to reduce certain side effects of chemotherapy, such as peripheral neuropathy (nerve damage) and oral mucositis (mouth sores). The rationale is based on Vitamin E's antioxidant properties, which may help protect normal cells from the oxidative damage induced by some chemotherapeutic agents. Several randomized controlled trials and meta-analyses have examined the effectiveness of Vitamin E, particularly alpha-tocopherol, in preventing chemotherapy-induced peripheral neuropathy (CIPN). Some studies suggest a modest benefit, especially in patients treated with cisplatin, paclitaxel, or other neurotoxic agents. However, results are mixed, and some experts caution that antioxidants might theoretically reduce chemotherapy effectiveness, though this has not been conclusively demonstrated. Gamma-tocopherol, specifically, is less studied than alpha-tocopherol, but it is sometimes included in Vitamin E supplements. The majority of research focuses on the general Vitamin E group or alpha-tocopherol. Despite this, clinical guidelines sometimes mention Vitamin E as a possible intervention for neuropathy, though not as standard of care. There is limited evidence supporting its use for other chemotherapy side effects. In summary, Vitamin E is used as a supportive intervention during chemotherapy based on scientific evidence, but the quality and consistency of that evidence are moderate, and there remains some controversy about its routine use.

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Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe

Products containing Vitamin E (gamma unspecified)

We currently have no products on Vitabase that contain this ingredient.