Evidence supporting the use of: Vitamin E (mixed)
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (mixed tocopherols and tocotrienols) has been studied for its potential to reduce certain side effects of chemotherapy, particularly chemotherapy-induced peripheral neuropathy (CIPN). This side effect involves nerve damage that can cause numbness, pain, or weakness, and is a significant concern for patients undergoing treatments with agents such as cisplatin or paclitaxel. Several small randomized controlled trials and meta-analyses suggest that Vitamin E supplementation may offer some protection against the development or severity of CIPN. For example, a 2017 systematic review in Supportive Care in Cancer and a 2020 meta-analysis in Frontiers in Oncology found modest benefit in reducing neuropathy incidence and severity, although results were not consistent across all studies. However, evidence supporting Vitamin E's ability to reduce other chemotherapy side effects (such as mucositis or general toxicity) is limited or negative. Additionally, concerns remain that antioxidant supplements like Vitamin E could theoretically reduce the effectiveness of some chemotherapeutic agents, although clinical confirmation of this is lacking. Most guidelines recommend caution and highlight the need for more robust, large-scale studies before routine use. In summary, there is some scientific evidence—though not strong or universally accepted—that Vitamin E may help reduce certain chemotherapy side effects, especially neuropathy, but further high-quality research is needed to confirm its efficacy and safety in this context.

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Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe

Products containing Vitamin E (mixed)

We currently have no products on Vitabase that contain this ingredient.