Evidence supporting the use of: Vitamin E (unspecified)
For the health condition: Chemotherapy (reducing side effects)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin E has been investigated for its potential to reduce certain side effects of chemotherapy, particularly chemotherapy-induced peripheral neuropathy (CIPN). Several small clinical trials have suggested that Vitamin E supplementation might decrease the incidence or severity of CIPN in patients receiving neurotoxic agents such as cisplatin or paclitaxel. For example, a randomized controlled trial published in Journal of Clinical Oncology (2003) found that patients receiving Vitamin E had a lower risk of developing neuropathy compared to placebo. Other studies, however, have shown mixed or inconclusive results, and some reviews note that the benefit may be modest and not consistent across all chemotherapy regimens or patient populations. Additionally, concerns exist regarding the concurrent use of antioxidants like Vitamin E with chemotherapy, as they might theoretically reduce the efficacy of certain chemotherapeutic agents by protecting tumor cells from oxidative damage. Major oncology guidelines, including those from ASCO and ESMO, do not currently recommend routine use of Vitamin E for chemotherapy side effect management due to insufficient high-quality evidence. Thus, while there is some scientific investigation and modest evidence supporting the use of Vitamin E for reducing specific chemotherapy-related side effects, the overall evidence base is limited, and routine use is not broadly endorsed.
More about Vitamin E (unspecified)
More about Chemotherapy (reducing side effects)
Other ingredients used for Chemotherapy (reducing side effects)
aloe veraalpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Milk Protein
Mistletoe
Other health conditions supported by Vitamin E (unspecified)
Age SpotsAlzheimer's Disease
Arteriosclerosis
Breast Lumps
Bruises (healing)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cataracts
Chemotherapy (reducing side effects)
Convalescence
Cuts
Dementia
Dermatitis
Diabetic Retinopathy
Free Radical Damage
Hair (loss or thinning)
Hepatitis
Inflammation
Macular Degeneration
Memory and Brain Function
Menopause